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OCR: ACTH is secreted episodically througho een seven twenty-four-hour period. There are betw ur during and thirteen episodes, most of which occ d and the second half of the normal sleep peric which are largely reproducible from one e cortisol twenty-four-hour period to another, Sin e exceptionand all of the adrenal androgens, with th al plasma TH, there of DHEA-sulphate, are responsive to AC are also episodic changes in the peripher hout the levels of these steroid hormones throug s cause this day (Fig. 7.9). It is not known what facto ogical pattern of ACTH release, and the physio ythm is advantage, if any, is also not clear. The r pattern, shifted by an alteration in the sleep-wak oss time such as that which occurs after travel acı i to zones, and five to seven days are require in rhythm com ...